Although very similar therapies, SRS delivers a large dose of radiation on a single day, while SRT has a fractionated treatment schedule. With SRT, treatment will span multiple days. While the total dose with SRT may be larger than in SRS, in any single day, patients undergoing SRT receive a smaller radiation dose. Cranial SRS or SRT is now the standard of care for benign and malignant brain tumors and numerous benign conditions, including arteriovenous fistulas, trigeminal neuralgia, and other pain conditions, as well as movement disorders such as Parkinson’s disease and epilepsy.
More recently, SRS and SRT are also being used extra-cranially, namely for locations outside the brain.